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Ultra-short-chain PFAS, such as TFA, are extremely polar and are poorly retained by conventional columns. We explain why they pose an analytical challenge and how Agilent Altura Poroshell 120 PFAS columns overcome retention, reduce system noise, and enable C1-C18 analysis in a single injection.

The rising baseline at the end of the temperature ramp in GC/MS has a name: column bleed. We explain why it occurs and how Agilent J&W 5Q columns (DB-5Q and HP-5Q) minimize it by combining Ultra Low-Bleed and Ultra Inert technologies.